Hidradenitis suppurativa
https://en.wikipedia.org/wiki/Hidradenitis_suppurativa
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References
What is hidradenitis suppurativa? 28209676 NIH
Hidradenitis suppurativa ke boemo ba letlalo bo sa foleng, bo lulang bo khutla, 'me bo ka ama bophelo ba hau hampe. E bakoa ke ho ruruha ka har'a mela ea moriri, 'me hangata e lebisa ho tšoaetso ea baktheria. Hangata lingaka li e hlahloba ka ho sheba mefuta ea liso tseo u nang le tsona (joaloka li-nodule, li-abscesses, kapa li-sinus tracts) , moo li leng teng (hangata li memenong la letlalo) , le hore na li khutla hangata hakae le hore na li tšoarella nako e kae.
Hidradenitis suppurativa is a chronic, recurrent, and debilitating skin condition. It is an inflammatory disorder of the follicular epithelium, but secondary bacterial infection can often occur. The diagnosis is made clinically based on typical lesions (nodules, abscesses, sinus tracts), locations (skin folds), and nature of relapses and chronicity.
Medical Management of Hidradenitis Suppurativa with Non-Biologic Therapy: What’s New? 34990004 NIH
Liphekolo tse sa sebelisetsoeng likokoana-hloko le tse se nang mekhoa ea phekolo li atisa ho sebelisoa li le mong bakeng sa lefu le bonolo 'me li ka kopanngoa le phekolo ea biologic le opereishene bakeng sa lefu le itekanetseng ho isa ho le matla. Liphuputso tsa morao-rao li fana ka bopaki bo eketsehileng ba katleho ea ho sebelisa corticosteroids e kentsoeng ka ho toba maqeba a HS flare-ups le maqeba a sebakeng seo. Ho feta moo, ho na le bopaki bo bontšang hore ho sebelisa tetracycline feela ho ka sebetsa hantle joalo ka ho kopanya clindamycin le rifampicin.
Non-biologic and non-procedural treatments are often used as monotherapy for mild disease and can be used in conjunction with biologic therapy and surgery for moderate to severe disease. Recent studies highlighted in this review add support for the use of intralesional corticosteroids for HS flares and localized lesions, and there is evidence that monotherapy with tetracyclines may be as effective as the clindamycin/rifampicin combination.
Hidradenitis Suppurativa: A Systematic Review and Meta-analysis of Therapeutic Interventions 30924446Liphekolo tse ngata li sebelisoa bakeng sa hidradenitis suppurativa, ho kopanyelletsa le lithibela-mafu, li-retinoids, li-antiandrogens, lithethefatsi tse thibelang ho itšireletsa mafung, meriana e thibelang ho ruruha, le radiotherapy bakeng sa liso tsa pele. Liphekolo tse khothaletsoang haholo ke adalimumab le laser therapy. Opereishene, ebang ke ho phunya ha bonolo kapa ho phunya ka ho feletseng sebakeng ka ho hlomathisa letlalo, ke khetho e ratoang bakeng sa linyeoe tse matla, tse tsoetseng pele tse sa arabeleng hantle liphekolong tse ling.
Many treatments are used for hidradenitis suppurativa, including antibiotics, retinoids, antiandrogens, immune-suppressing drugs, anti-inflammatory medications, and radiotherapy for early lesions. The top recommended treatments are adalimumab and laser therapy. Surgery, either simple excision or complete local excision with skin grafting, is the preferred option for severe, advanced cases that don't respond well to other treatments.
Hangata sesosa ha se tsejoe hantle, empa ho lumeloa hore se kenyelletsa motsoako oa liphatsa tsa lefutso le maemo a tikoloho. Hoo e ka bang karolo ea boraro ea batho ba tšoeroeng ke lefu lena ba na le setho sa lelapa se amehileng. Lintho tse ling tse kotsi li akarelletsa botenya le ho tsuba. Boemo ha bo bakoe ke tšoaetso, bohloeki bo bobe.
Ha ho tsejoe pheko. Ho seha maqeba ho a lumella ho tsoa ha ho hlahise molemo o moholo. Le hoja lithibela-mafu li atisa ho sebelisoa, bopaki ba tšebeliso ea tsona ha bo na thuso. Meriana ea Immunosuppressive le eona e ka lekoa. Ho ba nang le lefu le matla le ho feta, kalafo ea laser kapa opereishene ea ho tlosa letlalo le amehileng e ka sebetsa. Ke ka seoelo leqeba la letlalo le ka fetohang kankere ea letlalo.
Haeba linyeoe tse bonolo tsa hidradenitis suppurativa li kenyelelitsoe, joale khakanyo ea makhetlo a eona e tsoa ho 1-4% ea baahi. Basali ba kotsing ea ho fumanoa ba e-na le eona ka makhetlo a mararo ho feta banna. Hangata, ho qala ho hlaha lilemong tsa bocha.